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prego 0.0.10

  • Added return_all parameter to regress_pwm (multi-kmer path). When TRUE, returns every candidate-kmer regression (sorted by validation score) instead of just the best one - useful for getting N independent motifs without the residual-rounds approach used by motif_num > 1. When sample_for_kmers = TRUE, each candidate is refit on the full data.
  • Improved docs for regress_pwm (clarified the three operating modes, fixed n_motifs/comb_modle typos in the return-value section).

prego 0.0.9

  • Fix: Floating point discrepancies between predict and regress_pwm output.

prego 0.0.8

  • Fix: compute_local_pwm now returns NA when sequence length < motif length (issue #35).

prego 0.0.7

  • Fix: regress_multiple_motifs now works with multiple response variables.

prego 0.0.6

  • Added screen_local_pwm to find positions in sequences that match a PSSM.
  • Added return_list parameter to compute_local_pwm.

prego 0.0.5

  • Faster pssm correlation computation using RcppParallel.
  • pssm_match when best=FALSE now returns a score field instead of cor.
  • Implemented computation of KL divergence between two PSSMs. Note that spearman correlation is still the best way to match PSSMs.

prego 0.0.4

  • Added size paramter to intervals_to_seq.

prego 0.0.3

  • Added MotifDB object to store motif information.
  • Implmented a faster energy computation method, which is now used by default.

prego 0.0.0.9000

  • Added a NEWS.md file to track changes to the package.