Cluster guideRNAs

Source: R/compute.R

Clusters guides based on their target binding profile

clustGuides(guideSet, min_Son = 0, n_clust = 15, alpha = 10)

Arguments

guideSet

guideSet containing guide mappings
min_Son

Numeric from 0 through 1. Only considers genomic target binding sites above min_Son score.
n_clust

Integer from 1 to 20. Number of clusters to group guides into. Passed to cutree() function.

Value

guideSet object with clustered guides.

See also

addGuides(), and plotGuides()

Examples

if (FALSE) {
gs <- createGuideSet(Hsapiens, tes = te_annotation_df)
gs <- addTargets(gs, targets = 'LTR13A')
gs <- addGuides(gs, guide_length = 16)
gs <- compClusts(gs, min_Son = 0.25, n_clust = 10)
gs <- plotGuides(gs)
}